Estrogen Use Linked to Lower Death Rates in Women with UTIs: Major Study

Study Links Vaginal Estrogen to Lower Mortality Rates in Older Women with UTIs A new study presented at the American Urological Association's 2025 annual meeting in Las Vegas has revealed a significant correlation between the use of vaginal estrogen and lower mortality rates among women over 55 years old who experience recurrent urinary tract infections (UTIs). The study, which analyzed data from over 2 million women, showed that those using vaginal estrogen had substantially lower rates of sepsis (1.54% vs 10.6%) and mortality (0.42% vs 19.4%) compared to non-users. "While this is an observational study and doesn't establish direct causation," explains Dr. Kunal Sood, a board-certified MD, "the findings are notable and support what we already know about the benefits of vaginal estrogen in preventing recurrent UTIs." The study suggests a strong link between managing UTIs and overall health outcomes in postmenopausal women. Dr. Sood's video discussing the study has gained significant traction online, highlighting the public's interest in this research. The findings underscore the importance of comprehensive UTI management and the potential role of vaginal estrogen in improving the health and longevity of older women.