The "Sauce" and the Risks: How Performance-Enhancing Drugs Impact Tendons

In a recent TikTok video by @scientificsnitch, the topic of injuries among users of performance-enhancing drugs ("the sauce") is explored. The author explains that these substances suppress myostatin, a protein that plays a crucial role in both muscle growth and tendon health. While increased muscle mass is a desired outcome, the suppression of myostatin can lead to weaker tendons, resulting in a higher risk of injury. The video cites several research articles to support these claims. One study showed that myostatin mRNA expression was significantly inhibited by growth hormone, leading to increased muscle mass but potentially weaker tendons. Another study highlighted the importance of myostatin in tendon maintenance and repair. The video concludes that the risk of tendon-related injuries varies depending on the duration of drug use and individual genetic factors. This information underscores the importance of understanding the potential risks associated with performance-enhancing drugs and the need for responsible use and proper medical guidance.